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T833383β-Hydroxylanosta-8,24-dien-21-al;化合物 3β-Hydroxylanosta-8,24-dien-21-al3β-Hydroxylanosta-8,24-dien-2
3β-Hydroxylanosta-8,24-dien-21-al, a lanostane-type triterpene, exhibits tumor-promoting inhibitory effects by decreasing the incidence of papillomas in mice [1].
价 格:¥电议型 号:T83338产 地:中国大陆
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T8323LolCDE-IN-1;化合物LolCDE-IN-1LolCDE-IN-1
LolCDE-IN-1 is an inhibitor of the Lol proteins (LolCDE) complex. LolCDE-IN-1 shows antibacterial activity.
价 格:¥电议型 号:T8323产 地:中国大陆
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T83169Adenylyl cyclase-IN-1;化合物 Adenylyl cyclase-IN-1Adenylyl cyclase-IN-1
Adenylyl cyclase-IN-1 is a potential adenylyl cyclase inhibitor for ocular hypotonia research [1].
价 格:¥电议型 号:T83169产 地:中国大陆
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T83137ALP/Carbonic anhydrase-IN-1;化合物 ALP/Carbonic anhydrase-IN-1ALP/Carbonic anhydrase-IN-1
Compound 1e, also known as ALP/Carbonic anhydrase-IN-1, is a dual inhibitor targeting both carbonic anhydrase (CA) isozymes II, IX, and XII, as well as alkaline phosphatase (ALP). It exhibits inhibitory IC50 values of 0.44 ?M for CA-II, 1.61 ?M for CA-IX, 0.51 ?M for CA-XII, and 0.107 ?M for ALP [1].
价 格:¥电议型 号:T83137产 地:中国大陆
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T83120And1-IN-1;化合物 And1-IN-1And1-IN-1
And1-IN-1, also known as compound III, is a potent inhibitor of And1 [1].
价 格:¥电议型 号:T83120产 地:中国大陆
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T8310MMP-9-IN-1;化合物MMP-9-IN-1MMP-9-IN-1
MMP-9-IN-1 is an inhibitor of specific matrix metalloproteinase-9 (MMP-9).
价 格:¥电议型 号:T8310产 地:中国大陆
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T82965ARTD3/PARP3-IN-1;化合物 ARTD3/PARP3-IN-1ARTD3/PARP3-IN-1
ARTD3/PARP3-IN-1 is a non-selective inhibitor targeting diphtheria toxin-like ADP-ribosyltransferase 3 (ARTD3)/PARP3 [1].
价 格:¥电议型 号:T82965产 地:中国大陆
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T82950ATIC-IN-1;化合物 ATIC-IN-1ATIC-IN-1
ATIC-IN-1 (compound 14) serves as an inhibitor specifically aimed at the dimerization of Aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC), with a K i of 685 nM. This dimerization is essential for the enzyme´s aminoimidazole carboxamide ribonucleotide (AICAR) transformylase function. Furthermore, ATIC-IN-1 demonstrates anti-tumor properties by diminishing both cell proliferation and cell division rates [1].
价 格:¥电议型 号:T82950产 地:中国大陆
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T82945ATP Synthesis-IN-1;化合物 ATP Synthesis-IN-1ATP Synthesis-IN-1
ATP Synthesis-IN-1 (Compound 4), a quinoline derivative, potently inhibits PA ATP synthesis with an IC50 of 11.1μg/mL and exhibits antibacterial properties. This compound is utilized in studying drug-resistant PA infections [1].
价 格:¥电议型 号:T82945产 地:中国大陆
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T82944ATP Synthesis-IN-2;化合物 ATP Synthesis-IN-2ATP Synthesis-IN-2
ATP Synthesis-IN-2 (Compound 5) serves as a potent inhibitor of ATP synthesis activity, displaying significant antibacterial properties with an IC50 value of 0.7 μg/mL against Pseudomonas aeruginosa (PA) [1].
价 格:¥电议型 号:T82944产 地:中国大陆
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T82943AtPCO4-IN-1;化合物 AtPCO4-IN-1AtPCO4-IN-1
AtPCO4-IN-1 is a selective AtPCO4 inhibitor, exhibiting an IC50 value of 264.4 μM [1].
价 格:¥电议型 号:T82943产 地:中国大陆
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T82918BAX-IN-1;化合物 BAX-IN-1BAX-IN-1
BAX-IN-1 is a potential selective inhibitor of Bcl-2-associated X protein (BAX).
价 格:¥电议型 号:T82918产 地:中国大陆
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T82895Berlimatoxumab;化合物 BerlimatoxumabASN-2;ASN-2
Berlimatoxumab (ASN-2) is an antibody utilized for experimental research.
价 格:¥电议型 号:T82895产 地:中国大陆
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T82817Brevinin-1;化合物 Brevinin-1Brevinin-1
Brevinin-1, an antimicrobial peptide, originates from the skin secretions of the European green frog (Rana esculenta) [1].
价 格:¥电议型 号:T82817产 地:中国大陆
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T82814Brevinin-2;化合物 Brevinin-2Brevinin-2
Brevinin-2, an antimicrobial peptide, originates from the skin secretions of the European green frog (Rana esculenta) [1].
价 格:¥电议型 号:T82814产 地:中国大陆
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T82765CcpA-IN-1;化合物 CcpA-IN-1CcpA-IN-1
CcpA-IN-1 is a Staphylococcus aureus antibiotic exhibiting significant bactericidal activity (MICs=460 nM) [1].
价 格:¥电议型 号:T82765产 地:中国大陆
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T82758CDK9-Cyclin T1 PPI-IN-1;化合物 CDK9-Cyclin T1 PPI-IN-1CDK9-Cyclin T1 PPI-IN-1
CDK9-Cyclin T1 PPI-IN-1 (Compound B19) is a selective inhibitor of the CDK9-Cyclin T1 protein-protein interaction (PPI), suppressing cell proliferation in TNBC MDA-MB-231 cells with an IC50 of 0.044 μM and inducing apoptosis. This compound diminishes CDK9 transcriptional activity and downregulates phosphorylation of RNA Pol II CTD ser2. In vivo, CDK9-Cyclin T1 PPI-IN-1 effectively impedes tumor growth in a TNBC 4T1 mouse model [1].
价 格:¥电议型 号:T82758产 地:中国大陆
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T82731Cholesterol 24-hydroxylase-IN-2;化合物 Cholesterol 24-hydroxylase-IN-2Cholesterol 24-hydroxylase-IN-2
Cholesterol 24-hydroxylase-IN-2 is a potent inhibitor of cholesterol 24-hydroxylase (CH24H or CYP46A1), exhibiting an IC50 value of 5.4 nM, and has potential applications in mammalian imaging of this enzyme [1].
价 格:¥电议型 号:T82731产 地:中国大陆
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T82715Cisplatin-resistant cells-IN-1;化合物 Cisplatin-resistant cells-IN-1Cisplatin-resistant cells-IN-1
Cisplatin-resistant cells-IN-1 (Compound 8) exhibits high cytotoxicity against Cisplatin-resistant cells and effectively diminishes metabolic activity at low nanomolar concentrations, with an IC50 ranging from 0.14 to 1.79 μM in various resistant cell lines, including A549/A549-R, K562/K562-R, and MCF-7/MCF-7TamR [1].
价 格:¥电议型 号:T82715产 地:中国大陆
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T82635Cy-FBP/SBPase-IN-1;化合物 Cy-FBP/SBPase-IN-1Cy-FBP/SBPase-IN-1
Cy-FBP/SBPase-IN-1 (compound S5) serves as an inhibitor of the key regulatory enzyme Cy-FBP/SBPase in cyanobacterial photosynthesis, impeding the Calvin cycle and photosystem, thereby reducing photosynthetic efficiency. It effectively suppresses the proliferation of cyanobacteria, including Synechocystis sp. PCC6803, while demonstrating a safe profile in human-derived cell lines and zebrafish models [1].
价 格:¥电议型 号:T82635产 地:中国大陆